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2022 Feb

• How much are trans-acting enhancers responsible for regulating widely conserved functions (e.g. essential and house-keeping)? In a species with a recent expansion of TEs (and a larger genome size), will such enhancer regions still conserved in sequences but regulating from a longer distance?

  • Bergman, et al. (2022) Compatibility rules of human enhancer and promoter sequences. Nature doi:10.1038/s41586-022-04877-w

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